by marcbacon | Dec 1, 2019
Kaufmann W E, Sprouse J, Rebowe N, Hanania T, Klamer D, Missling C U Pharmacol Biochem Behav. 2019, December 187:172796. doi: 10.1016/j.pbb.2019.172796. Rett syndrome (RTT) is a severe neurodevelopmental disorder that is associated in most cases with mutations in the...
by marcbacon | Jul 9, 2019
Zeitler B, Froelich S, Marlen K, Shivak D.A, Yu Q, Li D, Pearl J.R, Miller J.C, Zhang L, Paschon D.E, Hinkley S.J, Ankoudinova I, Lam S, Guschin D, Kopan L, Cherone J.M, Nguyen B.H.O, Qiao G, Ataei Y, Mendel M.C, Amora R, Surosky R, Laganiere J, Vu B.J , Narayanan A,...
by marcbacon | Mar 1, 2019
Leahy E Drug Development & Delivery March 2019 Vol 19 No 2: 46-49. At the recent American College of Neuropsychopharmacology (ACNP) meeting, Sunovion Pharmaceuticals and PsychoGenics Inc. announced positive Phase 2 results for SEP-363856, a novel, first-in-class...
by marcbacon | Feb 1, 2019
Kwan M Y, Choo A, Hanania T, Ghavami A, Beltran J, Shea J, Barboza A, Hu A, Fowler M, Rao N V, Sucholeiki I Int J Mol Sci. 2019 Feb; 20(4): 811. Published online 2019 Feb 14. doi: 10.3390/ijms20040811. There is an unmet medical need for the development of...
by marcbacon | Oct 1, 2018
Lancaster, Li J, Hanania T, Liem R, Scheideler M. A, Scherer S. Experimental Neurology 2018 Oct;308:13-25. doi: 10.1016/j.expneurol.2018.06.010. Epub 2018 Jun 22. We have analyzed a mouse model of Charcot-Marie-Tooth disease 2E (CMT2E) harboring a heterozygous...