Preclinical Neuropathic Pain Models
We employ specialized models, techniques, and assessments to precisely evaluate the clinical significance of your potential breakthrough:
Nerve Ligation Models
PsychoGenics’ researchers employ well-established nerve ligation models, including spinal (L5/L6) nerve ligation (SNL), chronic constriction injury of the sciatic nerve (CCI), and spared nerve injury (SNI). These models mimic neuropathic pain conditions, enabling us to assess the effectiveness of potential interventions in alleviating pain symptoms.
Chemotherapy-Induced Neuropathic Pain
To assess chemotherapy-induced peripheral neuropathic pain, we utilize agents such as paclitaxel, bortezomib, oxaliplatin, and vincristine. These models enable us to gauge the efficacy of emerging therapies in mitigating chemotherapy-induced neuropathy.
