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Amyloid precursor protein induces reactive astrogliosis

by Desiree Cobb-Olori | Apr 29, 2025

A systematic assessment of robustness in CNS safety pharmacology

by Kelly Morris | Oct 10, 2024

Maria Reiber, Helen Stirling, Tim P. Ahuis, Washington Arias, Katharina Aulehner, Ute Dreßler, Martien J. H. Kas, Johanna Kela, Kimberly Kerker, Tarja Kuosmanen, Helga Lorenz, Alexander T....

Immunotherapy Targeting the C-Terminal Domain of TDP-43 Decreases Neuropathology and Confers Neuroprotection in Mouse Models of ALS/FTD

by marcbacon | Feb 20, 2023

The GBA1 D409V Mutation Exacerbates Synuclein Pathology to Differing Extents in two Alpha-Synuclein Models

by marcbacon | Aug 24, 2022

Heterozygous mutations in the GBA1 gene – encoding lysosomal glucocerebrosidase (GCase) – are the most common genetic risk factors for Parkinson’s disease (PD). Experimental evidence suggests a correlation between decreased GCase activity and accumulation of...

Elevation of brain magnesium with Swiss chard and buckwheat extracts in an animal model of reduced magnesium dietary intake

by marcbacon | Nov 4, 2021

Bassem F. El-Khodor, Karma James, Qing Chang, Wei Zhang, Yvette R. Loiselle, Chinmayee Panda & Taleen Hanania Nutritional Neuroscience. 2022 DOI: 10.1080/1028415X.2021.1995119, https://doi.org/10.1080/1028415X.2021.1995119 Objectives: Inadequate dietary magnesium...
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