by Desiree Cobb-Olori | Apr 1, 2025
Taleen Hanania, Herman Fernandes, Mei Kwan, Jose Beltran, John Shea, Afshin Ghavami Aims: rTg4510 mice conditionally express mutant human Tau in variousforebrain regions using Tet-off expression system. This model recapitulatestau pathology observed in AD with...
by Desiree Cobb-Olori | Mar 27, 2025
Taleen Hanania, Herman Fernandes, Mei Kwan, Jose Beltran, John Shea, Afshin Ghavami Objectives: rTg4510 mice conditionally express mutant human Tau in various forebrain regions using Tet-off expression system. This model recapitulates tau pathology observed in AD with...
by Desiree Cobb-Olori | Mar 27, 2025
Daniel Havas, Kristina Locker-Kovacovicova, Smriti Mongia Objective: Histological detection of amyloids in human and mouse brain tissue is complex. Fibril structures and aggregation lead to a reduction of relevant epitopes for primary antibody detection and some...
by Desiree Cobb-Olori | Mar 25, 2025
Alzheimer’s Disease (AD) is an increasingly prevalent neurodegenerative disorder that is typically recognized for the progressive cognitive dysfunction it induces. However, agitation, a term covering symptoms of restlessness, irritability, and verbal or physical...
by Desiree Cobb-Olori | Feb 6, 2025
NF-L is a validated biomarker for assessing disease progression, intensity, and treatment response across a wide range of neurodegenerative disorders including Alzheimer’s disease (AD), Parkinson’s disease (PD), Huntington’s disease (HD), amyotrophic lateral sclerosis...
