Epilepsy & Seizure Disorders

At PsychoGenics, we provide expert preclinical epilepsy and seizure disorder studies and services to help you discover your breakthrough therapy. Our capabilities cover EEG and behavioral identification of seizures. We excel in developing, executing, and analyzing complex rodent EEG studies. Our proficiency in interpreting intricate EEG data provides you with a distinctive edge, delivering the evidence required to propel your research forward. Our translational animal disease models have been well characterized to allow trusted efficacy investigations, ensuring understanding of your drug’s potential.

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Services

Services

Customized Preclinical Epilepsy and Seizure Disorder Study Design for Your Therapy

Collaborating closely with you, we design studies that precisely quantify the effect of your treatment. By tailoring the study to address your specific preclinical research needs, we ensure the collection of robust data that enhance your potential.

Preclinical Seizure Models

PsychoGenics provides seizure models based on behavioral and physiological assessments without EEG recordings. These models allow evaluation of seizure onset, duration, and severity using observable endpoints. Ideal for high-throughput and early-phase studies, they support compound screening and therapeutic profiling. Our assays help identify anticonvulsant potential and safety margins efficiently. Suitable for drug discovery and translational neuroscience research.

Dravet Syndrome

PsychoGenics is highly experienced in preclinical studies of Dravet syndrome, a rare and debilitating genetic disorder characterized by severe and prolonged seizures, typically beginning in infancy.

EEG Seizure

PsychoGenics offers epilepsy and seizure studies that utilize both EEG and behavioral seizure identification. With custom electrode configurations, ECoG, and local field potential (LFP) recordings from cortical and subcortical regions, we can record up to 64 rats or mice simultaneously.

Angelman Syndrome

PsychoGenics is dedicated to supporting your research and advancing your program with tailored preclinical Angelman syndrome studies.  Angelman syndrome is a neurodevelopmental disorder that emerges early in life, marked by developmental delays, intellectual challenges, and specific behavioral features.

Rett Syndrome

Rett syndrome is a neurodevelopmental disorder caused by mutations in the X-linked methyl CpG binding protein 2 (Mecp2) gene. Primarily affecting girls, it stands as a leading cause of intellectual disabilities. Preclinical studies of Rett syndrome are pivotal for advancing treatment development.

Tuberous Sclerosis

Tuberous sclerosis complex (TSC) is a rare genetic disorder that affects multiple organs, including the brain, leading to the formation of noncancerous tumors called tubers.

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