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A systematic assessment of robustness in CNS safety pharmacology.

Nutritional supplement containing a nuclear fraction of bovine thymus gland increases the circulating levels of spermidine

Target Validation Studies of PS48, a PDK-1 Allosteric Agonist, for the Treatment of Alzheimer’s Disease Phenotype in APP/PS1 Transgenic Mice

Developmental deletion of amyloid precursor protein precludes transcriptional and proteomic responses to brain injury

Swedish Alzheimer’s disease variant perturbs activity of retrograde molecular motors and causes widespread derangement of axonal transport pathways

Amyloid precursor protein induces reactive astrogliosis

A systematic assessment of robustness in CNS safety pharmacology

Immunotherapy Targeting the C-Terminal Domain of TDP-43 Decreases Neuropathology and Confers Neuroprotection in Mouse Models of ALS/FTD

The GBA1 D409V Mutation Exacerbates Synuclein Pathology to Differing Extents in two Alpha-Synuclein Models

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