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A systematic assessment of robustness in CNS safety pharmacology.

Nutritional supplement containing a nuclear fraction of bovine thymus gland increases the circulating levels of spermidine

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Measurement of cell proliferation by heavy water labeling.

Loss of erbB signaling in oligodendrocytes alters myelin and dopaminergic function, a potential mechanism for neuropsychiatric disorders.

Structure-based design leads to the identification of lithium mimetics that block mania-like effects in rodents. possible new GSK-3beta therapies for bipolar disorders.

Exploring neurocircuitries of the basal ganglia by intracerebral administration of selective neurotoxins.

Determination of the dopamine agonist rotigotine in microdialysates from the rat brain by microbore column liquid chromatography with electrochemical detection.

Mice with chronically elevated dopamine exhibit enhanced motivation, but not learning, for a food reward.

Monitoring brain chemical signals by microdialysis.

Discovery of novel hippocampal neurogenic agents by using an in vivo stable isotope labeling technique.

Beta-lactam antibiotics offer neuroprotection by increasing glutamate transporter expression.

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