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Effect of the Rd1 Mutation on Motor Performance in R6/2 and Wild Type Mice. PLoS Currents Huntington Disease.

Identification of Novel alpha4 beta2-Nicotinic Acetylcholine Receptor (nAChR) Agonists Based on an Isoxazole Ether Scaffold that Demonstrate Antidepressant-like Activity. Journal of medicinal chemistry.

Behavior-Based Screening as an Approach to Polypharmacological Ligands, in Polypharmacology in Drug Discovery.

R6/2 Huntington’s disease Mice Develop Early and Progressive Abnormal Brain Metabolism and Seizures.

Caspase-6 Activity in a BAC HD Mouse Modulates Steady State Levels of Mutant Huntingtin Protein but is not Necessary for Production of a 586 Amino Acid Proteolytic Fragment.

Behavior-based screening as an approach to polypharmacological ligands.

HD Mouse Models reveal clear Deficits in Learning to Perform a Simple Instrumental Response. PLoS Currents: Huntington Disease.

Discovery of Isoxazole Analogs of Sazetidine-A as Selective alpha4 beta2-Nicotinic Acetylcholine Receptor (nAChR) Partial Agonists for the Treatment of Depression,

Comparative psychology and the grand challenge of drug discovery in psychiatry and neurodegeneration,

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