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A systematic assessment of robustness in CNS safety pharmacology.

Nutritional supplement containing a nuclear fraction of bovine thymus gland increases the circulating levels of spermidine

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Sub-optimal performance in the 5-choice serial reaction time task in rats was sensitive to methylphenidate, atomoxetine and d-amphetamine, but unaffected by the COMT inhibitor tolcapone.

Mephedrone, compared to MDMA (ecstasy) and amphetamine, rapidly increases both dopamine and serotonin levels in nucleus accumbens of awake rats.

Circadian Abnormalities in Motor Activity in a BAC Transgenic Mouse Model of Huntington’s Disease.

Histopathological and neurological features of Atg4b knockout mice.

Dissociation between Duration of Action in the Forced Swim test in Mice and Nicotinic Acetylcholine Receptor Occupancy with Sazetidine, Varenicline, and 5-I-A85380.

The triple reuptake inhibitor DOV216,303 exhibits limited antidepressant-like properties in the differential reinforcement of low-rate 72-second responding assay, likely due to dopamine reuptake inhibition.

Male and female Fmr1 knockout mice on C57 albino background exhibit spatial learning and memory impairments.

The Novel triple reuptake inhibitor JZAD-IV-22 exhibits an Antidepressant Pharmacological profile without Locomotor Stimulant or Sensitization Properties.

Psychostimulant-like discriminative stimulus and locomotor sensitization properties of the wake-promoting agent modafinil in rodents.

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