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A systematic assessment of robustness in CNS safety pharmacology.

Nutritional supplement containing a nuclear fraction of bovine thymus gland increases the circulating levels of spermidine

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Regional Vulnerability in Huntington’s disease: fMRI-guided Molecular Analysis in Patients and a Mouse Model of disease

Comprehensive Behavioral and Molecular characterization of a new knock-in Mouse Model of Huntington’s disease: zQ175

Insights into the Structural Determinants Required for High Affinity Binding of Chiral Cyclopropane-Containing Ligands to α4β2-Nicotinic Acetylcholine Receptors; An Integrated Approach to Behaviorally Active Nicotinic Ligands.

Functional Improvement in Mouse Models of Familial Amyotrophic Lateral Sclerosis by PEGylated insulin-like Growth Factor I Treatment Depends on Disease Severity .

Prediction of Death in the SMNΔ Mouse Model of Spinal Muscular Atrophy: Insight into Disease Stage and Progression. Journal of Neuroscience Methods.

Identification of a Maleimide-Based Glycogen Synthase Kinase-3 (GSK-3) Inhibitor, BIP-135, that Prolongs the Median Survival Time of Ä7 SMA KO Mouse Model of Spinal Muscular Atrophy.

Effect of the Rd1 Mutation on Motor Performance in R6/2 and Wild Type Mice. PLoS Currents Huntington Disease.

Identification of Novel alpha4 beta2-Nicotinic Acetylcholine Receptor (nAChR) Agonists Based on an Isoxazole Ether Scaffold that Demonstrate Antidepressant-like Activity. Journal of medicinal chemistry.

Behavior-Based Screening as an Approach to Polypharmacological Ligands, in Polypharmacology in Drug Discovery.

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