Regional vulnerability in Huntington’s disease: fMRI-guided molecular analysis in patients and a mouse model of disease
Moreno H, Lewandowski N, Bordelon Y, Brickman A, Angulo S, Khan U, Muraskin J, Griffith E, Wasserman P, Menalled L,...
Characterization of Rat Kindling Models
Repeated sub-convulsive electrical stimulation of the rat amygdala or hippocampus induces seizures generate powerful models for seizure research. Amygdala kindling...
Preclinical Duchenne Muscular Dystrophy (DMD) Studies
At PsychoGenics, we provide transformative solutions for preclinical DMD research, driving rigorous scientific inquiry into this X-linked genetic disorder marked...
Preclinical Behavioral and In Vivo Testing Studies
PsychoGenics is a one-stop shop for CNS discovery services, with expertise in a broad range of capabilities from EEG to...
Disease Foundations
At PsychoGenics, we understand the complexities disease research foundations encounter in their pursuit of developing treatments. Our decades-long partnerships with...
ANAVEX®2-73 (blarcamesine), a Sigma-1 receptor agonist, ameliorates neurologic impairments in a mouse model of Rett syndrome
Kaufmann W E, Sprouse J, Rebowe N, Hanania T, Klamer D, Missling C U Pharmacol Biochem Behav. 2019, December 187:172796....
Characterization of a Mouse Model of Parkinson’s Disease
The Thy-1-α-synuclein mouse model of Parkinson’s disease is a transgenic mouse model that over-expresses wild-type human alpha-synuclein under the Thy1...
Characterization of a Mouse Model of CMT2E
The below data was made possible by CMTA, the Charcot-Marie-Tooth Association. Charcot-Marie-Tooth (CMT) disorders are a family of related disorders that...
The triple reuptake inhibitor DOV216,303 exhibits limited antidepressant-like properties in the differential reinforcement of low-rate 72-second responding assay, likely due to dopamine reuptake inhibition.
Paterson, N. E.; Balci, F.; Campbell, U.; Olivier, B. E.; Hanania, T. J Psychopharmacol.2011 Doi: 10.1177/0269881110364272. Epub 2010 Mar 19....
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Learn about PsychoGenics’ Capabilities and Disease Models Key Therapeutic Areas Our customized preclinical testing services and industry-leading models cover a...