Mephedrone, compared to MDMA (ecstasy) and amphetamine, rapidly increases both dopamine and serotonin levels in nucleus accumbens of awake rats.
Kehr, J.; Ichinose, F.; Yoshitake, S.; Goiny, M.; Sievertsson, T.; Nyberg, F.; Yoshitake, T. Br J Pharmacol
Comprehensive behavioral testing in the R6/2 mouse model of Huntington’s disease shows no benefit from CoQ10 or minocycline.
Menalled, L. B.; Patry, M.; Ragland, N.; Lowden, P. A.; Goodman, J.; Minnich, J.; Zahasky, B.; Park, L.; Leeds, J.;...
Comparison of Three Novel Neuroprotective Therapies for Traumatic Brain Injury Using a CCIModel in Rats
Johana Bastidas, Michael Lang, Rachel Barrett, Smriti Mongia, Daniel Havas, Taleen Hanania. Traumatic brain injury (TBI) is a major cause...
Characterization of The R6/1 Mouse Model of Huntington’s Disease
The B6.Cg-Tg(HD exon1)61Gpb/J mouse line, or R6/1, is a Huntington’s disease model that carries the human huntingtin gene’s 5’ end...
Phenotyping of a TDP-43 Mouse Model of ALS
Amyotrophic Lateral Sclerosis (ALS) is a fatal neurodegenerative disease characterized by progressive loss of upper and lower motor neurons producing...
Characterization of The rTg4510 Mouse Model of Alzheimer’s Disease
rTg4510 mice overexpress human tau containing the P301L mutation downstream of a tetracycline operon-responsive element (TRE). Expression is driven by...
Precision-Driven Preclinical Microdialysis Services
PsychoGenics’ preclinical microdialysis services offer capabilities in single or dual probe microdialysis studies. With our in-house bioanalytical experts, you benefit...
Preclinical Rare CNS Disorders Research
PsychoGenics offers specialized preclinical research services tailored to rare CNS disorders to drive your program forward. Leveraging our translational research...