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Publication – Phenotyping Transgenic Rodents

Oakeshott S, Balci F, Filippov I, Murphy C, Port R, Connor D, Paintdakhi A, Lesauter J, Menalled L, Ramboz S, Kwak S, Howland D, Silver R, Brunner D.
Circadian Abnormalities in Motor Activity in a BAC Transgenic Mouse Model of Huntington's Disease. PLoS Curr 2011, 3, RRN1225.

Read R, Savelieva K, Baker K, Hansen G, Vogel P.
Histopathological and neurological features of Atg4b knockout mice. Vet Pathol. 2011, 48, 486-94.

Baker K, Wray S, Ritter R, Mason S, Lanthorn T, Savelieva K.
Male and female Fmr1 knockout mice on C57 albino background exhibit spatial learning and memory impairments. Genes, Brain and Behavior 2010, 9, 562-574.

Menalled L, Patry M, Ragland N, Lowden P.A, Goodman J, Minnich J, Zahasky B, Park L, Leeds J, Howland D, Signer E, Tobin A.J, Brunner D.
Comprehensive behavioral testing in the R6/2 mouse model of Huntington's disease shows no benefit from CoQ10 or minocycline. PLoS One 2010, 5, e9793.

Menalled L, El-Khodor B.F, Patry M, Suarez-Farinas M, Orenstein S.J, Zahasky B, Leahy C, Wheeler V, Yang X.W, MacDonald M, Morton A.J, Bates G, Leeds J, Park L, Howland D, Signer E, Tobin A, Brunner D.
Systematic behavioral evaluation of Huntington's disease transgenic and knock-in mouse models. Neurobiol Dis 2009, 35, 319-36.

Ye G-L, Baker K.B, Mason S.M Zhang W, Kirkpatrick L, Lanthorn T.H, Savelieva K.V.
GABAa receptor α1 subunit (Gabra1) knockout mice: review and new results. In Mutant and Transgenic Tools in Modeling Brain Disorders, Kalueff, AV; Bergner, CL, Ed. Humana Press: 2009, 65-90.

Rajan I, Savelieva K.V, Ye G-L, Wang C-Y, Malbari M.M, Friddle C, Lanthorn T.H, Zhang W.
Loss of the putative catalytic domain of HDAC4 leads to reduced thermal nociception and seizures while allowing normal bone development. PLoS One 2009, 4(8), e6612.

Balci F, Papachristos E.B, Gallistel C.R, Brunner D, Gibson J, Shumyatsky G.P.
Interval timing in genetically modified mice: a simple paradigm. Genes Brain Behav 2008, 7, 373-84.

Savelieva K.V, Rajan I, Baker K.B, Vogel,P, Jarman,W, Allen,M, Lanthorn,T.H.
Learning and memory impairment in Eph receptor A6 knockout mice. Neuroscience letters 2008, 438, 205-209.

El-Khodor B.F, Edgar N, Chen A, Winberg M.L, Joyce C, Brunner D, Suarez-Farinas M, Heyes M.P.
Identification of a battery of tests for drug candidate evaluation in the SMNDelta7 neonate model of spinal muscular atrophy. Exp Neurol 2008, 212, 29-43.

Menalled L, Gomeniouk A, Brunner D, Leavitt B.R.
Huntington Disease In Animal and Translational Models of Behavioral Disorders Borsini, R. M. a. F., Ed. Elsevier: 2008.

Pogorelov V.M, Baker K.B, Malbari M.M, Lanthorn T.H, Savelieva K.V.
Standardized Behavioral Test Battery to Identify and Validate Targets for Neuropsychiatric Diseases and Pain. In Experimental models in neurobehavioral research, Kalueff AV, LaPorte JL, Ed. Nova Science Publishers: 2008, 17-46.

Savelieva K.V, Zhao S, Pogorelov V.M, Rajan I, Yang Q, Cullinan E, Lanthorn T.H.
Genetic disruption of both tryptophan hydroxylase genes strongly reduces serotonin in the brain and affects behavior in models sensitive to antidepressants. PLoS One 2008, 3(10), e3301.

Zhang W, Rajan I, Savelieva K.V, Wang C-Y, Vogel P, Kelly M, Xu N, Hasson B, Jarman W, Lanthorn T.H.
Netrin-G2 and netrin-G2 ligand are both required for normal auditory responsiveness. Genes Brain Behav. 2008,7(4), 385-92.

Menalled L.
Knock-in mouse models of Huntington's disease. NeuroRx 2005, 2, 465-70.

Ramboz S, Oosting R, Amara D.A, Kung H.F, Blier P, Mendelsohn M, Mann J.J, Brunner D, Hen R.
Serotonin receptor 1A knockout: an animal model of anxiety-related disorder. Proc Natl Acad Sci U S A 1998, 95, 14476-81.

 

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