Equipment includes:

  • Waters Acquity HPLC systems
  • Waters Quattro Premier XE triple quadrupole mass spectrometers
  • Eicom HTEC-500 HPLC-ECD instruments

Bioanalysis is performed on microdialysis samples from brain (whole, slices, regions) liver, kidney, plasma, CSF, and cell culture.

UPLC/MS/MS methods available for:

  • Acetylcholine, Choline, Histamine, Glutamate and GABA
  • Kynurenine, Kynurenic acid, Quinolinic acid and all metabolites
  • Lipids (ie. prostanoids, neurosteroids)
  • Adenosine (and other purines)
  • Compounds of interest (for PK and PK/PD correlations)

HPLC-ECD methods available for:

  • Monoamines: Dopamine, Noradrenaline, Serotonin and their metabolites (MHPG, DOPAC, HVA, 5-HIAA)
  • Amino acids: Glutamate, Aspartate, GABA, Glycine, Taurine
  • Acetylcholine

EIA, RIA methods available for:

  • Second messengers: cAMP, cGMP
  • Neuropeptides; proteins: fragments; soluble forms of Aβ peptides
  • Cytokines, interleukins, trophic factors, hormones, growth factors

Click on any of the tests for a complete description.

  • PsychoGenics
  • 765 Old Saw Mill River Road, Tarrytown, NY 10591
  • tel: (914) 406-8019
  • fax: (914) 593-0645