cubes

Abstracts / Posters

Society for Neuroscience – 2016

Rational design and development of ligands for the treatment of depression through partial agonism and desensitization of α4β2-nAChR: a collaborative project summary
B. EATON, O. K. ONAJOLE, L. YU, H. ZHANG, J. LIU, G. P. VALLERINI, W. TUECKMANTEL, V. ALEXANDROV, K. CAVINO, S. K. CHELLAPPAN, A. GHAVAMI, T. HANANIA, L. A. DAVID, M. MANZANO, N. E. PATERSON, C. RUIZ, E. SABATH, M. TERRY, L. THIEDE, D. WANG, P. WHITEAKER, M. NYS, C. ULENS, A. MAZZOLARI, G. VISTOLI, A. B. SMIT, B. J. CALDARONE, D. BRUNNER, R. J. LUKAS, A. P. KOZIKOWSKI … Abstract / Posters

Chronic Class IIa HDAC inhibition only partially replicates the beneficial effects of HDAC4 genetic reduction in HD models
O. AZIZ, C. A. LUCKHURST, T. HEIKKINEN, O. KONTKANEN, G. TOMBAUGH, S. GELMAN, D. YATES, K. MATTHEWS, R. WILLIAMS, P. BRECCIA, M. LAMERS, R. JARVIS, A. HAUGHAN, D. FISCHER, G. MCALLISTER, W. BLACKABY, A. GHAVAMI, G. OSBORNE, D. GOODWIN, G. BATES, I. MUNOZ-SANJUAN, C. DOMINGUEZ, L. PARK, M. MAILLARD, V. BEAUMONT … Abstract / Posters

In vivo characterization of CNS penetrant KMO inhibitor using microdialysis coupled with a novel high content LC/MS/MS method
G. SMAGIN, D. P. BUDAC, M. CAJINA, A. LEE, B. CAMPBELL, G. LI, C. SANCHEZ, C. FORRAY, V. S. PALAMARCHOUK, D. SONG … Abstract / Posters

Stable isotope labeled L-kynurenine (KYN) metabolism investigated using In vivo microdialysis coupled with a novel high content LC/MS/MS method
D. P. BUDAC, D. SONG, M. CAJINA, A. LEE, B. M. CAMPBELL, G. LI, C. SÁNCHEZ, C. FORRAY, V. S. PALAMARCHOUK, G. N. SMAGIN … Abstract / Posters

In vivo characterization of the cortico-basal ganglia connectivity in the zQ175 heterozygous knock-in mouse model of Huntington’s disease
S. ZHONG, A. GHAVAMI, R. CACHOPE, V. BEAUMONT … Abstract / Posters

14C-2-deoxyglucose autoradiography screen for mouse brain activity: relating known therapeutics and novel compounds for schizophrenia, depression, and bipolar disorder to brain circuitry
A. GIOVANNI, S. ENGEL, C. BOWEN, R. TERRY-LORENZO, P. G. JONES, L. HARDY, T. LARGE, T. HANANIA, E. V. SABATH, V. ALEXANDROV, M. QUTAISH, M. SEAMAN, P. CZARNECKI, M. SILVA, J. SULLIVAN … Abstract / Posters

Animal models of post traumatic stress disorder: behavioral characterization and pharmacological validation
I. MORGANSTERN, Q. CHANG, A. CHOO, L. THIEDE, K. HOMA, E. SABATH, W. ALVINS, J. SUTPHEN, S. DAVIS, J. BELTRAN, M. KWAN, D. BREGNA, G. SMAGIN, S. LEISER, A. GHAVAMI, T. HANANIA … Abstract / Posters

Propagation and aggregation of alpha synuclein in murine models
K. R. WALKER, W. ARIAS, J. BERGER, N. CHIRICHELLA, B. S. NUNEZ, R. SPRINGER, K. CIRILLO, J. SANCHEZ-PADILA, G. TOMBAUGH, A. GHAVAMI, S. RAMBOZ … Abstract / Posters

Synaptic alterations in direct and indirect pathway spiny projection neurons in the Q175 mouse model of Huntington’s disease.
J. SANCHEZ-PADILLA, G. TOMBAUGH, S. GELMAN, K. KRETSCHMANNOVA, J. PALMA, A. GHAVAMI, V. BEAUMONT, R. CACHOPE … Abstract / Posters

Differences in synaptic dysfunction between rTg4510 and APP_PS1 mouse model of Alzheimer’s disease
S. GELMAN, J. SANCHEZ-PADILLA, J. PALMA, P. KABITZKE, G. TOMBAUGH, A. GHAVAMI … Abstract / Posters


Alzheimer's Association International Conference – 2016

Differences between Tg2576 and APP/PS1 mice in high throughput behavioral screening correlates with differences in brain pathology
T. HANANIA, D. HAVAS, I. MORGANSTERN, E. SABATH, P. KABITZKE, M. MAZZELLA, K. COX, J. BERGER, M. WINDISCH, D. BRUNNER, V. ALEXANDROV … Abstract / Posters

Effects of treatment with Doxycycline on Behavior, Neuroinflammation and Brain Pathology in rTg4510 mouse model
D. HAVAS, M. WINDISCH, I. MORGANSTERN, P. KABITZKE, E. SABATH, L. THIEDE, M. MAZZELLA, D. BRUNNER, V. ALEXANDROV, T. HANANIA … Abstract / Posters

Differences in synaptic dysfunction between rTg4510 and APP/PS1 mouse models of Alzheimer's disease
S GELMAN, J PALMA, P KABITZKE, G TOMBAUGH, A GHAVAMI … Abstract / Posters


World CNS Summit – 2016

Early Detection and Characterization of Neurological Function in SOD1 G93A mice
I. MORGANSTERN, B. FERETIC, K. HOMA, S. MALEKIANI, M. NILGES, N. PATERSON, N. ROBERTS, E. SABATH, G. SARDARYAN, L. THIEDE, T. HANANIA … Abstract / Posters

Complementary phenotypic characterization of a genetically modified animal model of Parkinson’s Disease: Line 61
S. RAMBOZ, K. CIRILLO, R. SPRINGER, M. MAZZELLA, M. WINDISCH and K. WALKER … Abstract / Posters

 

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