Abstracts / Posters
Society for Neuroscience 2012
MJFF Animal Models 2: Phenotypic characterization of the autosomal recessive (Parkin, Pink-1 and DJ-1) gene knockout rat models of PD
K. D. DAVE, S.D. SILVA, S. RAMBOZ, M.J. BECK, C. QUANG, S.A. BENKOVIC, S.O. AHMAD, S. SUNKIN, D. WALKER, K. GAMBER, Y. AZIZ, M.A. BAPTISTA, S.S. DAS, A. DUFOUR, J.L. EBERLING, M.F. FACHERIS, N. SHETH, A. URKOWITZ, L. VINCENT, B.K. FISKE, T.B. SHERER, M. FRASIER … Abstract / Posters
Capturing New Chemical Space via Diversity Oriented Synthesis: the Discovery of Novel Histaminergic Modulators
J. R. DUVALL, J. T. LOWE, S. KESAVAN, L.A. MARCAURELLE, E. HOLSON, J. BEAUDOUIN, E. COMER, E. DAVOINE, K. DENNEHY, T. HANANIA, M. D. LEE, M LEWIS, D LOWE, J. C. MARIE, C. A. MULROONEY, G. MUNCIPINTO, T. PETRYSHEN, B. C. SUH, F. WAGNER, J. WEI, M. A. FOLEY … Posters
Early Behavioral Phenotypes of A Mouse Tauopathy Model and its Controls
D. BRUNNER, D.CONNOR, V. ALEXANDROV, V. ISTOMIN, M. DOLGUIKH, P.D.WES, E. SABATH, K. CAVINO, S. OAKESHOTT, T. HANANIA, D.M.BARTEN, N.X. BARREZUETA, M.K. AHLIJANIAN … Abstract
Rational Design and Development of Drugs for the Treatment of Depression through Partial Agonism and Desensitization of 4β2-Nicotinic Acetylcholine Receptors (nAChR): A Multi-disciplinary and Collaborative Approach
J. B.EATON, HAN-KUN ZHANG, LI YU, T HANANIA, E SABATH, A FEDOLAK, L LUCERO, D BRUNNER, A. P. KOZIKIWSKI, R. J. LUKAS … Abstract
Age-related Impairments in acquisition, reversal and intradimensional shift in a simple visual discrimination task in the zQ175 mouse model of Huntington’s disease.
N. PATERSON, B. ALOSIO, S. RAMBOZ, L.C. PARK, D. HOWLAND, D. BURNNER … Abstracts
An integrated approach to behaviorally active nicotinic ligands for use in depression.
L. YU, H.K. ZHANG1, J. EATON, M. NYS, A. MAZZOLARI, R. VAN ELK, A. B. SMIT, T. HANANIA, D. BRUNNER, R. J. LUKAS, G. VISTOLI, C. ULENS, A. P. KOZIKOWSKI … Abstracts
Dual single unit recording in Globus Pallidus (GP) and Subthalamic nucleus (STN) in anesthetized rats: a comparison of GP and STN firing patterns in wild type and BACHD transgenic rats.
S. ZHONG, G. TOMBAUGH, S.BENT, L. MRZLJAK, V. BEAUMONT, A. GHAVAMI … Abstracts
Hyper-excitability of the in-vivo hippocampal network in the R6/2 mouse model of huntington’s disease.
H. LIN, S. ZHONG, A. GHAVAMI, S. BENT, L. MRZLJAK, V. BEAUMONT, G. TOMBAUGH … Abstracts
Targeting Glycogen Synthase Kinase-3: An Integrated Approach to Bipolar Disorder Therapy.
H GUNOSEWOYO, I. N. GAISINA, T HANANIA, L THIEDE, A FEDOLAK, D BRUNNER, A MIDZAK, V PAPADOPOULOS, A. P. KOZIKOWSKI … Abstracts
High throughput behavioral assessment of analgesic compounds for neuropathic pain.
H. S. HAIN, S. F. DAVIS, A. Hu, V.V. ISTOMIN, M. C. IWUNZE, P. LORELLO, S.A. MALEKIANI, E.V. SABATH, V. ALEXANDROV, T. HANANIA … Abstracts
Behavioral Characterization of rats after Controlled Cortical Injury: Effects of Progesterone.
A. SINGH, J. LACSINA, H HAIN, T. HANANIA … Abstracts
Neurotrauma Meeting (Submitted) 2012
Possible effects of Progesterone in Bilateral Controlled Cortical Injury (BCCI) in rats.
A. SINGH, J. LACSINA, T. HANANIA … Abstracts
7th Annual Huntington's Disease Therapeutics Conference 2012
Impairment in reversal learning in a simple visual discrimination task in two mouse models of Huntington’s disease.
N.PATERSON, C. MURPHY, S.OAKSHOTT, D.HE, B.ALOSIO, K.MCCONNELL, L.MENALLED, S.RAMBOZ, D.HOWLAND, D.BRUNNER … Posters
Deficits in a visual go/no-go discrimination task in two mouse models of Huntington’s disease.
S. OAKSHOTT, R. PORT, J. SUTPHEN, J.BERGER, J. WATSON, S. RAMBOZ, D. HOWLAND, D. BRUNNER, … Posters
Deficits in Knock in Mouse Models of Huntington’s Disease Detected Using the Tapered Balance Beam Task.
A. KUDWA, J. TORELLO, J. FITZPATRICK, S. MILLER, R. MUSHLIN, V. ISTOMIN, M. DOLGUIKH, V. ALEXANDROV, D. BRUNNER, L. PARK, D. HOWLAND, S. RAMBOZ, L. MENALLED … Posters
Dual single unit recording in Globus Pallidus (GP) and Subthalamic nucleus (STN) in anesthetized rats: a comparison of GP and STN firing patterns in wild type and BACHD transgenic rats.
S. ZHONG, G. TOMBAUGH, S.BENT, L. MRZLJAK, V. BEAUMONT, A. GHAVAMI … Posters
Society for Neuroscience 2011
Pharmacological characterization of paclitaxel-induced neuropathic pain in rats.
S.A. MALEKIANI, W. HU, S.F. DAVIS, T. HANANIA … Abstract / Posters
Distinct neuropharmacological substrates mediate impulsive action and impulsive choice in rats.
NEIL E. PATERSON, CAITLIN WETZLER, ADRIAN HACKETT, TALEEN HANANIA … Posters
The Possible Role of Specific Vs Nonspecific iNOS Inhibitors After Thoracic Spinal Cord Injury In (SCI) Rats.
A. SINGH, J. LACSINA, T. HANANIA … Abstract / Posters
Evaluation of cognitive and social functions in rats subchronically treated with phencyclidine.
Q. CHANG, N. E. PATERSON, S. F. DAVIS, C. NATHAN COHRON, J. RICCIARDI, A. HACKETT, C. WETZLER, T. HANANIA … Abstract / Posters
Deficits in knock in mouse models of Huntington’s Disease detected using the tapered balance beam task
A. KUDWA, J. TORELLO, J. FITZPATRIC, S. MILLER, R. MUSHLIN, L. PARK , D. HOWLAND, S. RAMBOZ, L. MENALLED … Abstract
The BAC transgenic mouse model of Huntington’s disease exhibits cognitive deficits in a touchscreen operant assay
A. KUDWA, J. TORELLO, J. FITZPATRIC, S. MILLER, R. MUSHLIN, L. PARK , D. HOWLAND, S. RAMBOZ, L. MENALLED … Abstract
Motivational abnormalities in HD mouse models
OAKESHOTT S, PORT R, SUTPHEN J, WATSON-JOHNSON J, RAMBOZ S, KWAK S, HOWLAND D, BRUNNER D. … Abstract
Society for Neuroscience 2010
Identification of a common critical developmental time point between SMNΔ7 neonatal and novel adult mouse models for spinal muscular atrophy.
B. F. EL-KHODOR, S. RAMBOZ, D. KOBAYASHI, M. WINBERG … Abstract
CAG 190 knock-in mouse model of Huntington’s disease: behavioral and volumetric analysis.
A. KUDWA, C. MORIN, S. MILLER, J. FITZPATRICK, R. MUSHLIN, B. ALOSIO, D. HE, C. MURPHY, M. RUIZ, J. WATSON-JOHNSON, K. LEHTIMAKI, J. PUOLIVALI, J. YRJANHEIKKI, S. RAMBOZ, S. KWAK, L. PARK, E. SCHAEFFER, D. HOWLAND, L. MENALLED … Abstract
Human huntingtin supplementation ameliorated deficits detected in murine huntingtin knock down mice.
L. B. MENALLED, A. KUDWA, S. MILLER, J. FITZPATRICK, C. MORIN, D. HE, B. ALOSIO, D. FEVERSTON, W. ARIAS, K. HOMA, B. FERETIC, S. DAVIS, R. STEVENSON, J. WATSON-JOHNSON, C. MURPHY, J. PUOLIVALI, J. YRJANHEIKKI, M. HAYDEN, M. POULADI, R. GRAHAM, R. MUSHLIN, E. SCHAEFFER, L. PARK, D. HOWLAND, S. KWAK, S. RAMBOZ … Abstract
The acetylcholinesterase inhibitor donepezil improves learning in the R6/2 model of Huntington's disease.
C. A. MURPHY, W. ARIAS, A. CHEN, W. ALOSIO, D. HE, D. FEVERSTON, L. SANCHEZ, M. NELSON, S. BENT, R. MUSHLIN, J. WATSON-JOHNSON, L. MENALLED, S. RAMBOZ, E. SCHAEFFER, M. BECONI, L. PARK … Abstract
Society for Neuroscience 2009
Antidepressant-like Activity of AMOP-H-OH (‘SAZETIDINE-A’) in the Forced Swim TSest is Mediated by High Affinity Nicotinic Acetylcholine Receptors.
B.J. CALDARONE, M. MANZANO, A. C. FEDOLAK, N.E. PATERSON, A.P. KOZIKOWSKI, M.R. PICCIOTTO, B.E. OLIVIER, and A. GHAVAMI … Posters
Disrupted temporal control in the R6/2 mouse model of Huntington’s disease ’s disease with different CAG repeat lengths.
F. BALCI, A. ROONEY, S. M. OAKESHOTT, M. DAY, D. BRUNNER … Abstract
Interval timing in dopamine transporter (DAT) knockdown mice
D. BRUNNER, E. LUDVIG, R. ABNER, X. ZHUANG, P. POON, F. BALCI … Abstract
Peripheral infusion of the peptide hormone amylin and its clinical candidate analog, PSN0041, produces antidepressant effects without sexual side effects.
B. J. CALDARONE, C. MACK, T. HANANIA, D. BRUNNER, M. SAMANT, D. PARKES, V. SRIVASTAVA, M. HANLEY, P. MCGONIGLE, W. ROTE, B. OLIVIER, A. GHAVAMI … Abstract
Selective 5-hydroxytryptamine 2C receptor agonists derived from the lead compound tranylcypromine: Identification of drugs in several animal models of CNS related disorders.
S. CHO, N. H. JENSEN, A. M. SVENNEBRING, T. KUROME, S. KADARI, M. L. MANZANO, J. E. MALBERG, B. J. CALDARONE, L. ABDALLAH, L. H. TECOTT, B. L. ROTH, A. P. KOZIKOWSKI … Abstract
Behavioral evaluation of transgenic R6/2 mouse models of Huntington's disease with different CAG repeat lengths.
A. KUDWA, C. MORIN, J. LACSINA, Z. DING, D. HE, A. CHEN, A. PARACHIKOVA, C. LEAHY, M. RUIZ, C. ALEXA, R. MUSHLIN, M. PATRY, C. MURPHY, L. PARK, D. HOWLAND, S. RAMBOZ, L. MENALLED … Abstract
Therapeutic potential of peptide hormones for psychiatric disease: Antipsychotic behavioral profile following peripheral administration in rodents.
C. MACK, A. GHAVAMI, B. CALDARONE, T. HANANIA, J. MALBERG, B. CHICCA, V. SRIVASTAVA, P. MCGONIGLE, W. ROTE, M. HANLEY, D. BRUNNER … Abstract
Conditional knock-down of endogenous huntingtin in mice: Behavioral characterization.
L. B. MENALLED, S. MILLER, J. FITZPATRICK, A. KUDWA, C. MORIN, M. PATRY, M. TERRY, K. HOMA, B. FERETIC, T. HANANIA, A. PARACHIKOVA, R. MUSHLIN, K. LEHTIMAKI, J. PUOLIVÄLI, S. RAMBOZ, D. HOWLAND, S. KWAK … Abstract
Integrated phenotyping of R6/2 mice in an automated social environment.
S. OAKESHOTT, J. SHAMY, A. PAINTDAHKI, R. PORT, D. VELEDNITSKY, I. FILIPPOV, C. PATER, M. PATRY, L. MENALLED, C. MURPHY, V. ALEXANDROV, S. RAMBOZ, J. WATSON-JOHNSON, M. RUIZ, D. LAROSE, J.-S. VALOIS, D. HOWLAND, S. KWAK, D. BRUNNER … Abstract
The triple reuptake inhibitors DOV216,303 and JZAD-IV-22 differ in their discriminative stimulus and locomotor stimulant properties despite similar affinities at three monoamine transporters and similar neurochemical effects
N. E. PATERSON, D. BRUNNER, T. HANANIA, J. ZHOU, A. KOZIKOWSKI, B. OLIVIER, B. CALDARONE, A. GHAVAMI … Abstract
Ligation of spinal nerves L4 and L5 produces robust allodynia without major motor deficits in mice.
G.-L. YE, K. SAVELIEVA, K. B. BAKER, T. H. LANTHORN, I. RAJAN … Abstract
Society for Neuroscience 2008
Preclinical Psychopharmacological Properties of JZP-4, a Novel and Potent Mood Stabilizer
T. HANANIA, M. FOREMAN … Posters
Sensitization of Locomotor Activity in the mouse as a Potential Indicator of Abuse Liability
B.J. CALDARONE, C.M. RUIZ, M.L. MANZANO, A.C. FEDOLAK, J. ZHOU, B. OLIVIER … Posters
The Role of γ-aminobutyric acid (GABA) and Glutamate in Harmaline-Induced Tremors in Mice
M.FOREMAN, S.A. MALEKIANI, N.E. PATERSON and T. HANANIA … Posters
Society for Neuroscience 2007
Pharmacological Characterization of Harmaline-Induced Tremors in Mice
T. HANANIA, S.A. MALEKIANI, M. FOREMAN … Posters
Society for Neuroscience 2006
Comparison of Typical and Atypical Antipsychotics on PCP-Induced Hyperactivity in Mice
B.J. CALDARONE, M. NILGES, M.L. MANZANO, S.A. MALEKIANI, A.C. FEDOLAK, P. MCGINIGLE, and T. HANANIA … Posters
Effect of 5-HT1A Receptor Agonists on Marble Burying and Stress-Induced Hyperthermia in Mice
T. HANANIA, M.J. CANIGA, A.C. FEDOLAK, S.A. MALEKIANI, M.L. MANZANO, J.H. SCHNELKER, P. MCGINIGLE and B.J. CALDARONE … Posters
Society for Neuroscience 2005
Two Mouse Models with Predictive Validity for Treatment of Bipolar Disorder: Amphetamine/Chlordiazepoxide-Induced Hyperactivity and Prepulse Inhibition of Acoustic Startle
T. HANANIA, G.M. DILLON, S.A. MALEKIANI, M.L. MANZANO and E. LEAHY … Posters
